England will be the first country in the world to start vaccinating people against the sexually transmitted infection gonorrhoea.
It will not be available for everyone. The focus will mainly be on gay and bisexual men with a history of multiple sexual partners or an STI.
The vaccine is 30-40% effective, but NHS England hopes it will reverse soaring numbers of infections.
There were more than 85,000 cases in 2023 – the highest since records began in 1918.
Gonorrhoea does not always have symptoms, but they can include pain, unusual discharge, inflammation of the genitals and infertility.
How many people will chose to be immunised is uncertain.
But projections by Imperial College London show that if the jab proves popular then it could prevent 100,000 cases and save the NHS nearly £8m over the next decade, external.
Max, a sexual health campaigner, told BBC Newsbeat he would "100%" take the vaccine after being diagnosed with gonorrhoea twice within a year.
"I think this is great that it's been announced", he says, adding: "It's going to take the pressure off the clinics, it's just a big win all round."
Vaccination will start in August and will be offered through sexual health services.