Dozens sue saying Ozempic, other weight loss and diabetes drugs cause harmful side effects

[quote]Bronston and dozens of other patients are suing Eli Lilly and Novo Nordisk, the two companies that make drugs within this class of medication, saying they suffered distressing digestive symptoms, such as gallbladder removal or gastroparesis, after taking the drug.

Oh my god, their tummies hurt a bit and their gallbladders overreacted to not eating tons of garbage anymore, how awful! These fatties are going to ruin it for everyone, just as those freaks back in the day got an effective (and only!) Lyme disease vaccine out of production by insanely claiming it gave them arthritis.

Gastroparesis is nothing to make fun of, asshole at R1. It's a very serious condition that not much can be done for.

Millions of people are taking the drug. Most of them lose wight. A small subset of them get other illnesses during the time they're taking the weight loss drugs.

The trick is going to be proving that the other illnesses are a consequence of the meds. People have suffered from gastroparesis and have needed their gallbladders removed for years, long before Ozempic existed.

That's why I will never try weight loss drugs.

But they got thin, and in today's world that's all that matters.

It's better to look good than to feel good.

Remember when they introduced that "fat blocker" in the late 90s called Xenical?

It had side effects also, in fact it more or less invented the phrase "anal leakage".

Nothing can be that bad.

[quote]Millions of people are taking the drug.

And because the medication has only been around for a few years, there are no long term trials of the stuff.

You know what they say: Beauty is pain.

It's as safe Fen-Phen.

R7: "And because the medication has only been around for a few years, there are no long term trials of the stuff."

It's been on the market for 13 years, following the trials required to get it approved for sale. How long do the trials have to be?

[quote] It had side effects also, in fact it more or less invented the phrase "anal leakage".

I had a friend who was an adjunct professor somewhere in central Ohio. I went to visit her once and we drove down to Cincinnati to see one of her students do drag as OLESTRA: Complete with anal leakage!

What no anal leakage?

[quote]It's been on the market for 13 years, following the trials required to get it approved for sale. How long do the trials have to be?

It has not been "on the market" for 13 years.

"In June 2008, a phase II clinical trial began studying semaglutide." Note the word "studying"

"In 2012, a team of researchers at Novo Nordisk developed semaglutide for a once-weekly diabetes therapy as a longer-acting alternative to liraglutide. It was given the brand name Ozempic. Clinical trials started in January 2016 and ended in May 2017." Note the word "trials".

"In December 2016, the US FDA New Drug Application (NDA) was filed, and in October 2017, the FDA Advisory Committee approved it unanimously."

"In December 2017, the injectable version with the brand name Ozempic was approved for use by people with diabetes in the United States"

[quote] These fatties are going to ruin it for everyone

Who else needs these drugs?

BTW:

Ozempic is a medication approved for managing diabetes. It is currently not approved for weight loss in the EU.

I have been taking these drugs for a year and a half and have lost 45 lbs. i feel great and my health numbers are vastly improved, including no longer being pre-diabetic. Yes, I had some mild side effects. But the benefits have far outweighed the very moderate negative side effects I have experienced.

R16 How long will you need to take the drug?

What happens if you stop taking the dug?

Do you take other prescription medications as well? Over the long term do we know how all of the drugs will interact with one another?

R17: 1. Probably for life. New versions, including oral tablets, are in development that will be simpler to take than injections. 2. I have read that people regain the lost weight. 3. Yes, BP and cholesterol meds. There are no reported interactions between the GLP-1s and those meds.

R5 I had side effects. I didn’t realize how bad I felt until I got off. Insulin is much better for me.

I take it for diabetes. Not for weight loss. It works fine. I just wish it was priced accordingly - less for those with diabetes and more for those Fat Whores who can’t put the fork down.

Shocking! Like I've been saying, if something seems too good to be true - it probably is.

[quote]1. Probably for life.

I can understand for diabeties. But for weight loss, when you can diet and exercise?

It will be interesting to see what complications, what damage, will arise after decades of taking that stuff. Plus combined with all the other shit Americans take.

What will your quality of life be like at 70? Maybe it would be best to develop healthy choices now: diet, exercise, sleep, instead of relying on Big Pharma to do the hard work.

Tracy Morgan said he gained 40 lbs. taking it. I won't link to the Fail but you can find the story there.

More than 100 US deaths linked to Ozempic and similar weight loss drugs - including 28-year-old who died from 'intestinal mass' and a pregnant woman, our analysis shows

"have needed their gallbladders removed for years"

That's not how the gallbladder works, sweetie. When you need your gallbladder removed, they remove it. I had mine removed many moons ago and it was because it suddenly felt like I was having a heart attack.

Gallstones are common with any significant weight loss. I lost around 70lbs from ages 15-17, on my own, and I had to have my gallbladder removed at just 20!

Does it really matter? Many people will not lose weight and this might keep them from having a leg amputated, and keep everyone from having to pay for the effects of diabetes, LITERALLY millions are slowly dying from diabetes and we all pay for it. We will pay one way or another.

All drugs cause side effects.

When you get a side effect, call your doctor, make a follow-up appointment, and don’t take the medication until you see your dr.

One genius took two different versions of the medication and died.

Discovery is a bitch.

P.S. There are side effects to being a huge fat-ass!

[quote]It had side effects also, in fact it more or less invented the phrase "anal leakage".

I remember it as “anal seepage.”

Wait, but you gain the weight back? So you have to take this shit forever? That seems so....I don't know, daunting. Why can't you then keep the weight off? What about it makes you lose weight and why is it unsustainable?

I don't think it is a big deal to have to take a medication indefinitely.

Frankly, it kind of pisses me off that I eat right and exercise and work hard to maintain a normal weight when other people just jab themselves with drugs and then go eat cheesecake and shit.

R35 But they have to take that shit forever or they gain weight back, so don't be too jealous. It sounds like a bad deal to me.

The medication kills the urge to overeat until you pop. It is being considered for drunks and gambling addicts.

Fraus on this thread never met a pill they didn't pop or symptom they never had.

[quote]I don't think it is a big deal to have to take a medication indefinitely.

All those prescription drug commercials have really done job on you.

Hint: Try skipping 2nd dinner.

R32 The opposite. Your stool is euphemistically referred to by the staff at the clinic as "rabbit pellets." You have to hydrate and fiber, more than ever, is your friend. It's not for everyone but used as advertised it works as advertised.

My doc gave it to me as an alternative to insulin for diabetes. Ozempic requires one painless self-injection weekly vs. multiple insulin shots daily. My A1C levels are mid-4's which is not-diabetic-level blood sugar control. The amount of self-care is reduced and thus compliance is increased.

My insurance covers it. It's not all joy: nausea and vomiting are common side effects for some people. I'm eating better seeing what it does but I've only lost 3 or 4 pounds over 10 months. The endocrinologist thinks she can reduce the dose after a year, either as a smaller dose weekly or less frequent (bi-weekly) dosing.

R3$, stopping people from engaging in compulsive activity is difficult. It’s not enough to tell people “you should just stop” or “you need Jesus in your life” or whatever. It could be that this drug, or drugs like it, can actually address alcoholism and compulsive gambling, which are amazingly destructive. Life is hard enough. People shouldn’t have to suffer if they don’t have to.

I'm SHOCKED, I tell you. SHOCKED.

You mean a drug that messes with your digestive system and the body's ability to absorb food caused gastrointestinal problems, you know, like the side effects it warned about causing?

I am completely blindsided by this.

It’s a given just about any long term drug will cause SE… some worse than others

[quote] So you have to take this shit forever

I’ve been taking my arthritis medication for years and expect I’ll take it until I die. I have take it twice a day.

This weight loss medication only needs to be taken once a week.

I would never want to be on a medication for the rest of my life. Shit happens. If you lose your health insurance, how will you afford it? If they are already finding people are dying from it, why risk it when you could at least try to do it the healthy way. The people who should be taking this are the morbidly obese. At least it would give them a head start so that if they ever decided to exercise they could actually do so without the pain that being that obese causes.

Anyone who is taking it to lose less than 50 lbs just needs to get off their ass.

[quote] If they are already finding people are dying from it

They’re not.

Only one person died because she surreptitiously got 2 prescriptions of 2 different GLP1 meds from 2 different doctors. She overdosed herself.

What will the Hollywood starlets do now?!!

More than 100 US deaths linked to Ozempic and similar weight loss drugs - including 28-year-old who died from 'intestinal mass' and a pregnant woman

I got rid of 45lbs of useless weight and I didn’t have to resort to using drugs.

[quote]Ozempic and similar weight loss drugs

Meaning which drugs?

R46 But it sounds like it wouldn't give them a head start cause they'd gain it all back as soon as they're off it. We've all seen the people on Dr. Now who start losing weight but then the next week are suddenly up a few pounds at first until their gain is more than their loss.

R49 I asked about intestinal mass on the other thread, it sounded confusing but now I'm wondering if it was "an" intestinal mass, like a tumor?

These weight loss drugs do seem too good to be true. I’m curious to see how things will unfolding few years.

[quote]I’m curious to see how things will unfolding few years.

It's Fen-Phen and Olestra in a single injection.

Fen Phen was so clearly speed. Were we not supposed to know? Or what was the big controversy? I had a friend who had a prescription and he gave me one, I took it in the morning and was still flying high by 9 pm.

It absolutely was speed, r55. It also burned holes in people's hearts. I remember it, too being called a "miracle drug."

Yes R56! I dabbled in the occasional copious amounts of blow, so I could tell it was speed, but I guess other people didn't know? How could they not? I have a friend who lives in Ecuador and she just got prescribed a diet drug called Vistaril. She took it once and told me that it made her speedy and crazy and she hated it. I looked it up, and of course, it's phentermine. I guess it's still available in other countries.

Phentermine is still available in the US, R57.

It is R58? Wow, I figured it was verboten now after the whole big controversy with them in the 90s. Good to know, I guess. How come people don't take that instead of Ozempic? I mean, if they're both dangerous anyhow...

Phentermine is fine. It works as an appetite suppressant. Fenfluramine was the problem.

R59, it's not dangerous to most people.

Any drug is dangerous to some people, so why does anyone take anything? Because if they don't have any contraindications, they and/or their doctor, decide the potential benefits outweigh the risks.

Phentermine was never as effective as the GLP-1 drugs are. Even fewer people tolerated the side effects of phentermine, even when it wasn't used in combination with fenfluramine. Since it's an amphetamine, it has high potential for abuse. It's hard to predict who will have mood issues/behavior changes on speed. Tolerance to phentermine happens relatively quickly and a regular doctor (not a strip mall weight loss clinic but a real doctor) limits the number of months they're willing to prescribe it. When the weight loss stops on phentermine, the doctor pulls the prescription right away, the withdrawals are nasty (like with stopping any upper), and the person gains all the weight back.

R35 You can’t eat cheesecake on Ozempic and lose weight, that is not how it works. If you still eat the same crappy food as before you will not lose weight and have undesirable GI side effects.

[quote]You can’t eat cheesecake on Ozempic and lose weight, that is not how it works. If you still eat the same crappy food as before you will not lose weight

So just go on a diet.

You can eat cheesecake on Ozempic, you just won't eat very much and you won't enjoy it as much and the sweetness may make you too nauseated to eat for the rest of the day.

That's true, r63. A friend of mine is on it and she still eats crappy food. She's lost some weight but then she eats junk food and wonders why she isn't losing more. The truth of ANY diet is that unless your habits change for good and forever, there isn't much that can help you. Thinking of Ozempic as some wonder drug that allows you to eat whatever the fuck you want and not gain weight is an issue for a lot of people who don't want to do the work of changing their diet. They don't lose as much weight as the ones who are taking it and also being mindful with diet and exercise.

I would LOVE for there to someday be a drug like that...one where you can eat whatever and however much you wanted and not gain a single pound. But that's never going to happen in our lifetime. I would take Ozempic except that I don't want yet another drug to take. I already give the pharmaceutical companies enough money. And I've lost my weight with just diet and exercise which, even if one is on Ozempic, you still have to do. Maybe my weight loss would be higher/faster but I'm ok with the gradual burn I've been doing. 86 lbs lost over a year and a half is something I'm very proud of.

Great, now the Diabetic people who ACTUALLY need these drugs will have a harder time getting them thanks to vain people who wanted to be slim without wanting to change their habits and notions of eating at all.

The same way junkies ruined opioids for people with excruciating chronic pains.

R57: Vistaril isn’t a diet med. Perhaps your friend has the wrong name.

“Vistaril (hydroxyzine pamoate) is an antihistamine with anticholinergic (drying) and sedative properties used as a sedative to treat anxiety and tension. Vistaril is also used together with other medications given for anesthesia. Vistaril may also be used to control nausea and vomiting, or to treat allergic skin reactions such as hives or contact dermatitis. Vistaril is available in generic form.“

R1, people literally cannot shit. One person tried taking that crap you take for a colonoscopy prep and they still couldn’t go.

[quote] Great, now the Diabetic people who ACTUALLY need these drugs

You have to be diabetic to get it under 99% of insurances.

I just visited my friend, she's been taking this for about 3 months. She can't shit. She pukes too.

What about all the celebrities that DL accuse of being on Ozempic R69?

They’re fat, r71. Most fat people are diabetic or pre-diabetic.

^^^^

Not true.

R67 Shit, you're right, not vistaril, now I can't remember! Anyhow, it was basically 7.5 phentermine.

Most of the people taking semaglutide for weight loss are taking compounded semaglutide from a compounding pharmacy, not the branded diabetic medication made by Novo Nordisk, et al. Diabetics get the name-brand stuff from major pharmaceutical companies.

Semaglutide for weight loss, while approved, is not widely covered by insurance yet, and the name-brand stuff, which is sold under different names than the diabetic stuff, is prohibitively expensive for most people in the long term. For people who want to use semaglutide for weight loss, many choose compounded semaglutide, which is more affordable out of pocket, and it doesn't interfere with these pharmaceutical behemoths' supplies at all. '

From R75's link:

[quoteThe FDA told DailyMail.com on the figures previously: 'While FDA relies on the FAERS database as a drug safety surveillance tool after a product is approved and marketed, submission of a report does not mean that the information included in it has been medically confirmed.

[quote]'The event may have been related to the underlying disease being treated, or caused by some other drug being taken concurrently, or occurred for other reasons.'

[quote] They added: 'Duplicate reports and heightened awareness of an event with a particular product may inflate the reported occurrence of an adverse event.'

[quote] In comparison to the 100 deaths linked to weight loss drugs every year, there are 16,000 attributed every 12 months to NSAIDS — non-steroidal anti-inflammatory drugs used to treat pain and inflammation such as ibuprofen and aspirin.

Forgive me, I have to repost this since I messed it up. From R75's link:

[quote] The FDA told DailyMail.com on the figures previously: 'While FDA relies on the FAERS database as a drug safety surveillance tool after a product is approved and marketed, submission of a report does not mean that the information included in it has been medically confirmed.

[quote] 'The event may have been related to the underlying disease being treated, or caused by some other drug being taken concurrently, or occurred for other reasons.'

[quote] They added: 'Duplicate reports and heightened awareness of an event with a particular product may inflate the reported occurrence of an adverse event.'

[quote] In comparison to the 100 deaths linked to weight loss drugs every year, there are 16,000 attributed every 12 months to NSAIDS — non-steroidal anti-inflammatory drugs used to treat pain and inflammation such as ibuprofen and aspirin.

[quote]In comparison to the 100 deaths linked to weight loss drugs every year, there are 16,000 attributed every 12 months to NSAIDS — non-steroidal anti-inflammatory drugs used to treat pain and inflammation such as ibuprofen and aspirin.

I saw this coming a mile away! I've been telling you all that your Aleve was killing you and see I was right! I told you so! I told you so!

(Remember the "mark my words" troll?)