Well, I liked it. A lot - and I don't usually go for cutesy, quirky, or broad stereotypes. Haven't watched it in a few years, but it was fresh and funny and charming, plus I much preferred this fake fantasy of NYC life than Friends', it was a little more yuppie-skewing and yet darker in tone, I would have loved to live like them. It lost its way in the over-guested last 2 seasons but was still always at least entertaining and well written. The pop culture references (a staple of the sitcom format) were always more intelligent and less mainstream than those of its peers. And I found the acting to be fine. Shelley Morrison gave terrific deadpan, McCormack was a solid comic 'straight man' and balanced that well with the zanier moments, and Mullally was a great scene stealer and differentiated Karen from the obvious Patsy clone she was written as with her childlike mannerisms. Sean Hayes is an amazing physical comedian and had some surprisingly moving moments ("I'm not very good, am I?" at his cringeworthy acting audition), whilst Messing deservingly was compared to Lucille Ball - that dinner party double episode with Leo's ex (played by Mira Sorvino) where Grace quickly unravels was a whirlwind display of hysterical comedy.
Compared to other contemporaries, it wasn't as smug and self-important as Fraiser, as flat and unappealing as Mad About You, had more scope than The Nanny and Just Shoot Me, and had a lot of heart that Seinfeld lacked. It's dated very well despite the changing gay community - shit, even as a '90s sitcom' it stands very close to the top, if you're criticising it as a 'gay sitcom' you're being ridiculous: nothing else since has either it's height of quality or its longevity. Maybe Will's sexuality was eased into the show, but hell, well into its run I was shocked to see a gay interracial kiss (McCormack and Taye Diggs) and relationship on Network TV without it being made into a big deal or political statement. Look, even 'Empire' and the like can't manage that a decade later.
And while the guests got tiring, the work from people like Gene Wilder, Eileen Brennan, Lily Tomlin, Parker Posey, Minnie Driver, Lesley Ann Warren, Blythe Danner, Debbie Reynolds, Sandra Bernhard, Leslie Jordan, Molly Shannon, Sydney Pollack, Janet Jackson, Glenn Close, James Earl Jones, Demi Moore, John Cleese, Shohreh Aghdashloo, Coco Peru, Rosanna Arquette, Emily Rutherfurd (one of the best recurring guests), J. Lo, Alec Baldwin, Christine Ebersole, Kevin Bacon, Patti LuPone, Britney Spears, Rip Taylor, Joan Collins, Macaulay Culkin, Laura Kightlinger, Cher, Michael Douglas, Tim Bagley, Edie Falco+Chloe Sevigny (a GREAT offbeat pairing), Dan Futterman, Sara Gilbert, Natasha Lyonne, Candice Bergen, Madonna, Bobby Cannavale, Woody Harrelson, Gregory Hines, Leigh-Allyn Baker, Veronica Cartwright, Beau Bridges, Michael Angarano, Rosie O'Donnell, Nicollette Sheridan, Bernadette Peters, Ellen Albertini Dow, Suzanne Pleshette, Geena Davis, Alan Arkin, John Slattery, Jeff Goldblum, Camryn Manheim, Dylan McDermott, Tracey Ullman, Wanda Sykes, Sharon Stone, the list goes on and on. Great, often NYC-based actors who sometimes gave career best work, sometimes got to do something way outside their comfort zone, and were always well cast.