Hello and thank you for being a DL contributor. We are changing the login scheme for contributors for simpler login and to better support using multiple devices. Please click here to update your account with a username and password.

Hello. Some features on this site require registration. Please click here to register for free.

Hello and thank you for registering. Please complete the process by verifying your email address. If you can't find the email you can resend it here.

Hello. Some features on this site require a subscription. Please click here to get full access and no ads for $1.99 or less per month.

Baldness Cure (for Men & Women) in 2 years?

A lotion that cures male-pattern baldness could be for sale in as little as two years. University of Pennsylvania dermatologist George Cotsarelis says the lotion works by inhibiting a single enzyme, prostaglandin D2 (PGD2), which he says is the "major" enzyme connected to hair loss.

And the cure would also extend to men of all ages who have already lost their hair.

"We really do think if you remove the inhibition, you get longer hair," Cotsarelis told the journal Science Translational Medicine.

Cotsarelis and his team of researchers first applied the lotion to mice and found that it was effective in both stopping hair loss and in regenerating follicles that had already ceased to produce longer hairs.

"During normal follicle cycling in mice, Ptgds and PGD2 levels increase immediately preceding the regression phase, suggesting an inhibitory effect on hair growth," the study reads. "We show that PGD2 inhibits hair growth in explanted human hair follicles and when applied topically to mice."

Cotsarelis says he is currently shopping the lotion to several U.S. drug firms and hopes the product can be sold publicly in the near future.

He says that there are already prescription antiasthma drugs available, which work by reducing PGD2 levels. The presence of those treatments should help accelerate the baldness cure's availability in stores. The transition from discovery to potential product has already been a rapid one, as the study results were only first announced in March.

"I can't see why we won't soon be able to intervene to prevent hair loss," Des Tobin, the director of the University of Bradford Centre for Skin Sciences told the Telegraph, calling the study "a big step forward."

Offsite Link
by Anonymousreply 45February 13, 2021 11:22 PM

Oh, thank heavens.

by Anonymousreply 1September 4, 2012 2:33 AM

They're waiting until I'm completely bald before they put the cure out there.

by Anonymousreply 2September 4, 2012 2:39 AM

This is a definite step forward. Usually a baldness cure is about 5 or 10 years away from tomorrow, and tomorrow never comes.

by Anonymousreply 3September 4, 2012 2:40 AM

Safe for ballsacks?

by Anonymousreply 4September 4, 2012 2:41 AM

Great news for us eldergays ... eventually. Considering the market for this, it will be hugely expensive as long as the patents last.

by Anonymousreply 5September 4, 2012 2:42 AM

"it will be hugely expensive"

If it truly works (and not just Propecia-like effectiveness), then people will complain about the price, but pay. They'll mortgage their homes and pay.

by Anonymousreply 6September 4, 2012 2:47 AM

WEHT the stem cell cure? I've been waiting for that for 5 years already.

by Anonymousreply 7September 4, 2012 2:50 AM

if you've seen jason alexander lately, I think he got in on the trials.

by Anonymousreply 8September 4, 2012 2:50 AM

Great. Wake me when they cure cancer.

by Anonymousreply 9September 4, 2012 2:51 AM

I, for one, am not celebrating this. I love a bald man.

by Anonymousreply 10September 4, 2012 2:52 AM

Cool!

by Anonymousreply 11September 4, 2012 2:53 AM

Will it work on a completely bald head or is it like Propecia where it would only keep the hair you have?

by Anonymousreply 12September 4, 2012 2:54 AM

Yes, R6, those who can certainly will.

by Anonymousreply 13September 4, 2012 2:54 AM

What the drug company will do is set the price so it is high enough for them to make an obscene profit, and just high enough for consumers to reluctantly but willing pay the price.

by Anonymousreply 14September 4, 2012 2:58 AM

Did you read the article, R13?

[quote]And the cure would also extend to men of all ages who have already lost their hair.

by Anonymousreply 15September 4, 2012 3:00 AM

Tutti a tavola a pettinarsi!

by Anonymousreply 16September 4, 2012 3:03 AM

OK that was strange. At R15 I seem to be replying to myself at R13 with an unrelated comment, but I swear there was another post I was responding to that isn't showing up for me now. Maybe the board will sort itself out soon.

by Anonymousreply 17September 4, 2012 3:05 AM

If it's based on an existing drug then a generic version could possibly be made.

by Anonymousreply 18September 4, 2012 3:07 AM

Here's the positive and negative part:

1) Positive: The drug is already being prescribed in pill form to treat other conditions. It's passed the FDA review, so it might be faster to get it approved in lotion form. It's not some new, unknown drug.

2) Negative: No human trials, no concrete results, just a university-affiliated dermatologist shopping around a drug/cure to big drug companies.

So we can remain hopeful, but skeptical until trials on humans are performed.

by Anonymousreply 19September 4, 2012 3:08 AM

I like male-pattern baldness

by Anonymousreply 20September 4, 2012 3:10 AM

I'm going to buy a jug of the stuff and force my way into porn studios to lather up all those barren crotches.

by Anonymousreply 21September 4, 2012 3:11 AM

Yeah, but the side effects will be that you're balls shrivel down to raisinette size.

by Anonymousreply 22September 4, 2012 3:13 AM

I guess I understand this but I'm kind of shocked that so many view this as a great thing.

I think that bald or partially bald men are really handsome.

by Anonymousreply 23September 4, 2012 3:25 AM

No, I didn't read the article. TL;DR.

What did it say?

by Anonymousreply 24September 4, 2012 3:26 AM

Who cares, I don't need it.

by Anonymousreply 25September 4, 2012 3:33 AM

One's doctor knows which asthma drugs are described in the artcle. No one needs to wait for the high priced lotion. I've used minoxodil for 28 years and started when I had to buy the pills and have the pharmacist compound the stuff in a solution.

by Anonymousreply 26September 4, 2012 4:12 AM

It'll cause cancer. Don't you worry 'bout that!

by Anonymousreply 27September 5, 2012 12:58 PM

R25 you are awesome!

by Anonymousreply 28September 5, 2012 1:09 PM

[quote]We really do think if you remove the inhibition, you get longer hair,"

That's all the proof I need...somebody who THINKS something will work without any scientific data proving it. As long as someone thinks it then it is a fact!

by Anonymousreply 29September 5, 2012 1:14 PM

There have been lots of new medicines, promising miracle results for many problems, that never work.

If they have genuinely invented a medication to reverse pattern baldness, buy stock in the company, it is a practically a license to print money.

by Anonymousreply 30September 6, 2012 1:02 PM

A cure for baldness? I didn't know it was a disease.

by Anonymousreply 31September 6, 2012 1:09 PM

I just use the other end of my NO NO for more hair.

by Anonymousreply 32September 8, 2012 7:39 PM

Hello,

It would be great thing if it happens in near future. People are wondering really whether there is a proper treatment for baldness cure or not.

Offsite Link
by Anonymousreply 33March 26, 2013 5:13 AM

Thicker bushes too? They thin as you age as well.

by Anonymousreply 34March 26, 2013 5:53 AM

R7, I think PRP uses stem cells. Most people say it doesn't work though.

by Anonymousreply 35March 26, 2013 6:35 AM

will probably be as successful as that weight loss cureall, Alli.

by Anonymousreply 36March 26, 2013 6:43 AM

If a hair falls out (you don't see it on the head) is there still a little hair present there under the skin.

by Anonymousreply 37March 28, 2013 12:51 AM

Does it work on body hair?

by Anonymousreply 38March 28, 2013 1:15 AM

I'm on my way. See you tomorrow.

by Anonymousreply 39March 28, 2013 1:20 AM

Hairless Man Grows Full Head Of Hair In Yale Arthritis Drug Trial

Offsite Link
by Anonymousreply 40June 19, 2014 7:04 PM

Link to story.

Offsite Link
by Anonymousreply 41June 19, 2014 7:04 PM

r40 I really can't tell without seeing him smile.

by Anonymousreply 42June 19, 2014 7:11 PM

R40, the patient had alopecia, not arthritis.

by Anonymousreply 43June 19, 2014 7:21 PM

Since the OP cure didn't work out 8 years later...hopefully this will.

A team of researchers from Japan might have discovered the cure for baldness. The RIKEN Center for Biosystems Dynamics Research used stem cells and a specific culture mechanism to create hair follicles that can recycle hair just like natural follicles.

The researchers used stem cells to create hair follicles that can regrow hair after it falls out. That’s how hair growth should function. Hair loss is natural, but every strand of hair should be replaced by a new one that regrows in its place. The RIKEN Center for Biosystems Dynamics Research scientists published a paper in Nature Scientific Reports (via Futurism) detailing their progress with stem cells on mammals.

They took fur and whisker cells from mice and then cultured them in the lab together with other ingredients. They used 220 combinations, finding that one type of collagen paired with five factors (NFFSE medium) would lead to the highest rate of stem cell amplification in the shortest period of time. The RIKEN team explained that a successful hair-regeneration treatment that could cure baldness must produce hair that recycles. That means the hair can regrow after falling out naturally.

These researchers combined bioengineered hair follicle stem cells with the NFFSE medium, as well as with the medium missing one of the ingredients. They observed the regenerated hair for three weeks and discovered that the NFFSE medium allowed the hair follicles to go through at least three cycles of normal hair production. The other medium wasn’t nearly as efficient, with 79% of follicles producing only one hair cycle.

“Our culture system establishes a method for cyclical regeneration of hair follicles from hair follicle stem cells and will help make hair follicle regeneration therapy a reality in the near future,” Takashi Tsuji, the lead author of the study, said.

Offsite Link
by Anonymousreply 44February 13, 2021 11:19 PM

Well, hurry up!

by Anonymousreply 45February 13, 2021 11:22 PM
Loading
Need more help? Click Here.

Yes indeed, we too use "cookies." Take a look at our privacy/terms or if you just want to see the damn site without all this bureaucratic nonsense, click ACCEPT. Otherwise, you'll just have to find some other site for your pointless bitchery needs.

×

Become a contributor - post when you want with no ads!