Baldness Cure (for Men & Women) in 2 years?
A lotion that cures male-pattern baldness could be for sale in as little as two years. University of Pennsylvania dermatologist George Cotsarelis says the lotion works by inhibiting a single enzyme, prostaglandin D2 (PGD2), which he says is the "major" enzyme connected to hair loss.
And the cure would also extend to men of all ages who have already lost their hair.
"We really do think if you remove the inhibition, you get longer hair," Cotsarelis told the journal Science Translational Medicine.
Cotsarelis and his team of researchers first applied the lotion to mice and found that it was effective in both stopping hair loss and in regenerating follicles that had already ceased to produce longer hairs.
"During normal follicle cycling in mice, Ptgds and PGD2 levels increase immediately preceding the regression phase, suggesting an inhibitory effect on hair growth," the study reads. "We show that PGD2 inhibits hair growth in explanted human hair follicles and when applied topically to mice."
Cotsarelis says he is currently shopping the lotion to several U.S. drug firms and hopes the product can be sold publicly in the near future.
He says that there are already prescription antiasthma drugs available, which work by reducing PGD2 levels. The presence of those treatments should help accelerate the baldness cure's availability in stores. The transition from discovery to potential product has already been a rapid one, as the study results were only first announced in March.
"I can't see why we won't soon be able to intervene to prevent hair loss," Des Tobin, the director of the University of Bradford Centre for Skin Sciences told the Telegraph, calling the study "a big step forward."
Offsite Linkby Anonymous | reply 45 | February 13, 2021 11:22 PM
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They're waiting until I'm completely bald before they put the cure out there.
by Anonymous | reply 2 | September 4, 2012 2:39 AM
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This is a definite step forward. Usually a baldness cure is about 5 or 10 years away from tomorrow, and tomorrow never comes.
by Anonymous | reply 3 | September 4, 2012 2:40 AM
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Great news for us eldergays ... eventually. Considering the market for this, it will be hugely expensive as long as the patents last.
by Anonymous | reply 5 | September 4, 2012 2:42 AM
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"it will be hugely expensive"
If it truly works (and not just Propecia-like effectiveness), then people will complain about the price, but pay. They'll mortgage their homes and pay.
by Anonymous | reply 6 | September 4, 2012 2:47 AM
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WEHT the stem cell cure? I've been waiting for that for 5 years already.
by Anonymous | reply 7 | September 4, 2012 2:50 AM
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if you've seen jason alexander lately, I think he got in on the trials.
by Anonymous | reply 8 | September 4, 2012 2:50 AM
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Great. Wake me when they cure cancer.
by Anonymous | reply 9 | September 4, 2012 2:51 AM
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I, for one, am not celebrating this. I love a bald man.
by Anonymous | reply 10 | September 4, 2012 2:52 AM
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Will it work on a completely bald head or is it like Propecia where it would only keep the hair you have?
by Anonymous | reply 12 | September 4, 2012 2:54 AM
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Yes, R6, those who can certainly will.
by Anonymous | reply 13 | September 4, 2012 2:54 AM
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What the drug company will do is set the price so it is high enough for them to make an obscene profit, and just high enough for consumers to reluctantly but willing pay the price.
by Anonymous | reply 14 | September 4, 2012 2:58 AM
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Did you read the article, R13?
[quote]And the cure would also extend to men of all ages who have already lost their hair.
by Anonymous | reply 15 | September 4, 2012 3:00 AM
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Tutti a tavola a pettinarsi!
by Anonymous | reply 16 | September 4, 2012 3:03 AM
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OK that was strange. At R15 I seem to be replying to myself at R13 with an unrelated comment, but I swear there was another post I was responding to that isn't showing up for me now. Maybe the board will sort itself out soon.
by Anonymous | reply 17 | September 4, 2012 3:05 AM
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If it's based on an existing drug then a generic version could possibly be made.
by Anonymous | reply 18 | September 4, 2012 3:07 AM
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Here's the positive and negative part:
1) Positive: The drug is already being prescribed in pill form to treat other conditions. It's passed the FDA review, so it might be faster to get it approved in lotion form. It's not some new, unknown drug.
2) Negative: No human trials, no concrete results, just a university-affiliated dermatologist shopping around a drug/cure to big drug companies.
So we can remain hopeful, but skeptical until trials on humans are performed.
by Anonymous | reply 19 | September 4, 2012 3:08 AM
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I like male-pattern baldness
by Anonymous | reply 20 | September 4, 2012 3:10 AM
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I'm going to buy a jug of the stuff and force my way into porn studios to lather up all those barren crotches.
by Anonymous | reply 21 | September 4, 2012 3:11 AM
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Yeah, but the side effects will be that you're balls shrivel down to raisinette size.
by Anonymous | reply 22 | September 4, 2012 3:13 AM
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I guess I understand this but I'm kind of shocked that so many view this as a great thing.
I think that bald or partially bald men are really handsome.
by Anonymous | reply 23 | September 4, 2012 3:25 AM
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No, I didn't read the article. TL;DR.
What did it say?
by Anonymous | reply 24 | September 4, 2012 3:26 AM
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Who cares, I don't need it.
by Anonymous | reply 25 | September 4, 2012 3:33 AM
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One's doctor knows which asthma drugs are described in the artcle. No one needs to wait for the high priced lotion. I've used minoxodil for 28 years and started when I had to buy the pills and have the pharmacist compound the stuff in a solution.
by Anonymous | reply 26 | September 4, 2012 4:12 AM
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It'll cause cancer. Don't you worry 'bout that!
by Anonymous | reply 27 | September 5, 2012 12:58 PM
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[quote]We really do think if you remove the inhibition, you get longer hair,"
That's all the proof I need...somebody who THINKS something will work without any scientific data proving it. As long as someone thinks it then it is a fact!
by Anonymous | reply 29 | September 5, 2012 1:14 PM
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There have been lots of new medicines, promising miracle results for many problems, that never work.
If they have genuinely invented a medication to reverse pattern baldness, buy stock in the company, it is a practically a license to print money.
by Anonymous | reply 30 | September 6, 2012 1:02 PM
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A cure for baldness? I didn't know it was a disease.
by Anonymous | reply 31 | September 6, 2012 1:09 PM
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I just use the other end of my NO NO for more hair.
by Anonymous | reply 32 | September 8, 2012 7:39 PM
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Hello,
It would be great thing if it happens in near future. People are wondering really whether there is a proper treatment for baldness cure or not.
Offsite Linkby Anonymous | reply 33 | March 26, 2013 5:13 AM
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Thicker bushes too? They thin as you age as well.
by Anonymous | reply 34 | March 26, 2013 5:53 AM
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R7, I think PRP uses stem cells. Most people say it doesn't work though.
by Anonymous | reply 35 | March 26, 2013 6:35 AM
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will probably be as successful as that weight loss cureall, Alli.
by Anonymous | reply 36 | March 26, 2013 6:43 AM
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If a hair falls out (you don't see it on the head) is there still a little hair present there under the skin.
by Anonymous | reply 37 | March 28, 2013 12:51 AM
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Does it work on body hair?
by Anonymous | reply 38 | March 28, 2013 1:15 AM
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I'm on my way. See you tomorrow.
by Anonymous | reply 39 | March 28, 2013 1:20 AM
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Hairless Man Grows Full Head Of Hair In Yale Arthritis Drug Trial
Offsite Linkby Anonymous | reply 40 | June 19, 2014 7:04 PM
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r40 I really can't tell without seeing him smile.
by Anonymous | reply 42 | June 19, 2014 7:11 PM
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R40, the patient had alopecia, not arthritis.
by Anonymous | reply 43 | June 19, 2014 7:21 PM
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Since the OP cure didn't work out 8 years later...hopefully this will.
A team of researchers from Japan might have discovered the cure for baldness. The RIKEN Center for Biosystems Dynamics Research used stem cells and a specific culture mechanism to create hair follicles that can recycle hair just like natural follicles.
The researchers used stem cells to create hair follicles that can regrow hair after it falls out. That’s how hair growth should function. Hair loss is natural, but every strand of hair should be replaced by a new one that regrows in its place. The RIKEN Center for Biosystems Dynamics Research scientists published a paper in Nature Scientific Reports (via Futurism) detailing their progress with stem cells on mammals.
They took fur and whisker cells from mice and then cultured them in the lab together with other ingredients. They used 220 combinations, finding that one type of collagen paired with five factors (NFFSE medium) would lead to the highest rate of stem cell amplification in the shortest period of time. The RIKEN team explained that a successful hair-regeneration treatment that could cure baldness must produce hair that recycles. That means the hair can regrow after falling out naturally.
These researchers combined bioengineered hair follicle stem cells with the NFFSE medium, as well as with the medium missing one of the ingredients. They observed the regenerated hair for three weeks and discovered that the NFFSE medium allowed the hair follicles to go through at least three cycles of normal hair production. The other medium wasn’t nearly as efficient, with 79% of follicles producing only one hair cycle.
“Our culture system establishes a method for cyclical regeneration of hair follicles from hair follicle stem cells and will help make hair follicle regeneration therapy a reality in the near future,” Takashi Tsuji, the lead author of the study, said.
Offsite Linkby Anonymous | reply 44 | February 13, 2021 11:19 PM
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