I know there was a thread a couple of years ago, but I was wondering if anyone has done it in the past year and if the results have been better.
It's now $99 - which seems like a bargain to get SOME info on your genetic predisposition.
Originally this test cost $499 a few years back, so I'm happy to see it come down in price.
Does it tell you if you have the gene that makes you immune to HIV?
R1 - yes, it does.
It's pretty much the same, OP. And yes, R1. I'm not immune but supposedly I'm immune to a few things but I can't remember what they were.
They've added more diseases and things. I'm always being updated about something or other. I do wonder about the accuracy of their genetic picture or whatever it's called. I'm African American/Creole with two African American/Creole parents and I'm being told that I'm 53% European. To those of you who have purchased 23andMe, do you believe that the genetic picture/painting is accurate? I'm thinking about trying another company. Which companies are the most accurate?
[quote]It's pretty much the same, OP. And yes, [R1]. I'm not immune but supposedly I'm immune to a few things but I can't remember what they were.
Obviously, dementia is not one of them.
Ha! You got me, R5.
R4 - I think that's the exciting aspect of this - the more people that do it, the more info they have which could lead to some breakthroughs (hopefully).
I do remember this being over $1000 when it first came out, but Sergei Brin put in more funding last year to keep the cost down and to encourage more people to take it.
Now at $99, fuck it, I'm going to try it.
Do these tests indicate whether you might have a predisposition for say specific types of cancer by any chance? That would be pretty damned amazing,.
R8 - yes and no. If the normal population has a 4% chance of a specific cancer, it will tell you how much higher of a predisposition you have.
But, if you have a 50% higher genetic predisposition and only 4% of the population gets it, then your risk is 6%. (That's at least how one of the bloggers explained it).
You'll have to look up some of the people who have blogged about it. Overall, for $99, I think it sounds worth it.
It also gives you some ancestral data and can link you up with others that share a high percentage of the same data - usually 3rd or 4th cousins - from potentially around the world.
Interesting - if you scroll down, it can identify if you have HIV immunity (both genes), or if you have a slower progression to AIDS (one gene) or if you are like most people (neither gene present).
23andMe is owned by Google co-founder Sergey Brin's wife Anne. He just left her for some 20 something skank attention whore in his office
R4 Out of curiosity, what do you look like?
Does it tell you the percentage of Neanderthal admixture you have?
Call me paranoid, but I have always been wary of giving up my DNA info to some company. You see how people abuse your email address. Can you imagine how much someone would pay to get access to people's DNA records?
Especially if they are connected to Google. R19...
My test found I have a Romanian blood disorder - where did that come from and what could it mean?
And you wonder why it's only $99? They're selling your information. YOU are the product here.
R21 Do you look like Ivan Lyndl?
Is it easy to use a fake name?
R24 - Yes, you can use a fake name.
How are you going to use a fake name and then pay with your credit card & shipping address?
None of this information is of interest or use to me. Knowing that I may have a 6% instead of 4% chance of getting some cancer is not useful. I do what I can to live a healthy lifestyle. Nothing else I can do at this point.
And I'm certainly not spending a hundred bucks for useless info.
I did the test, but I could really give a rat's ass about the medical stuff.
I did it for genealogical purposes, to find out more about my family tree.
Found a few new branches this way, plus proved once and for all that a branch of our family was not African American. (Would have been happy either way, but was hoping to separate fact from rumor.)
Is this different than the DNA test available through ancestry.com?
Not terribly, R29. I've taken that one too.
R28, so you have faith that the Ancestry Painting is 100% accurate? Do you mind if I ask you why that is? Have you tested your ancestry with other companies? Do you believe that 23andMe is the most accurate? The map thing appears to say that I have a lot of Irish and German/Israeli/Middle Eastern ancestors ( I've even had what appears to be German people contacting me saying they are distant cousins). However, I'm African American/Creole and I'm very well aware of my French/Spanish ancestry ( I have older relatives who are VERY pro-France). I don't know anything about German ancestors. I don't know what to believe. I'm hoping someone here knows something about these things.
Does the ancestry.com do the health factors, too, or just the genealogical info?
It does, R18.
I've never seen any health factor info in the Ancestry DNA Analysis
"I'm African American/Creole and I'm very well aware of my French/Spanish ancestry ( I have older relatives who are VERY pro-France). I don't know anything about German ancestors. I don't know what to believe."
r31, you do realize that people from France and Spain can have German ancestry, don't you? European migrations, intermarriages and European multiculturalism go back tends of thousands of years and have never stopped.
R4/R31, I'm no expert on these things but from what I've read 23andMe is one of the more reputable and accurate DNA testing companies. You likely have some German or Jewish ancestry that you aren't aware of. Given that you are Creole and assuming that you or your ancestors are/were from Louisiana or the surrounding areas, the Irish, German and/or Jewish ancestry isn't surprising given the history of that area.
Regarding 53% European and/or Caucasian ancestry, it simply means that 53% of your recent ancestors were Caucasian. Genetics don't always work the way we think it does or should and considering your heritage it's entirely possible that it is accurate.I suggest that you join ancestry.com and maybe you'll be able to find out more about your ancestors and it may answer many of your questions.
R35 does have a good point. I know that the French like to believe that they are 100% French but many if not most are not.
I discovered that I'm 40.5% "nonspecific European." Why can't they be more specific? And I'm also 1/4 Polish but 23 and Me says I'm only 2.3% Eastern European. Odd.
I'm just afraid they'll find out I'm one-quarter Schnauzer.
Only a quarter, dear?
No, Lena. They found out you're 100% asshole.
[quote]Only a quarter, dear?
He's Polish..probably a third.
R31, I am biracial (my mother is German and my father is African American). My grandmother on my fathers side always said that her ancestors were Ethiopian Jews, and that they were sold into slavery by accident. She was raised in Texas, and was high yellow. She was actually debutante of the month in Jet magazine back in the day. I honestly thought that this information was bullshit, and thought that the family history at some point made up these facts because they wanted to distance themselves from the slave trade. My father did the DNA test through African ancestry, and we have relatives (within 8 generations) in Israel, but they are Libyan Jews. It is amazing that oral tradition could be passed down through generations and slavery. I would really like to find a reputable company to test myself.
What's the other 60%, R37? Yeah, it sucks that it isn't more specific, but as someone else mentioned they do have an ancestry map. But I hear ancestry.com is better in terms of finding out more about your ancestry. I think 23andMe is good for their information about diseases.
I would have to think the undefined European must be central European where there may have been more mixing about.
Just a guess.
R43: The other 60% includes the small percentage of Eastern European + 36% Southern European (my father was 100% Italian), 20% French and German (this was news to me) and less than 1% of south Asian, East Asian and Native American, and Sub-Saharan African. Does everyone basically have that 1% of Asian/African?
R44: I thought that, too. Especially with the way Poland would appear and disappear from the map throughout history.
I'm not sure. Mine was just a little higher at 2% Sub-Saharan and 4% Asian. However, a friend of mine did it and his ancestry painting showed that he had 9% Sub-Saharan African ancestry and 6% Asian. His ancestors came to America in the 1700s so that could explain the higher percentages.
Any access you give to ancestry.com, you give to the Mormons.
You're genetics are now locked in a vault in a mountain crypt in Utah somewhere.
Those fuckers are nervy creeps.
I've written a long blog article about my ancestry.com DNA results and how I processed the raw data through gedmatch.com for much more interesting results. You might want to read the blog. Gedmatch has many tools you can use to look at your results in different ways.
R50 - wow - there goes the anonymity of this board, Mr. Bob Atchison.
Not that you seem to care, but you never see real names on this board.
Hope you don't regret it.
Oh, and BTW, interesting article. Thanks.
You were hot in the 70s or 80s when that profile pic was taken. Love the pornstache.
I would be wary about the results of 23andme and other direct-to-consumer testing. Studies on these tests have shown that such testing need more regulation to prevent consumers from being confused or misled.
This is because there is a tremendous lack of information available to properly interpret many of these complex traits that are tested. These tests only look for markers, and clinical application of this information is limited because of either fragmentary or complete lack of data linking these markers with actual diseases.
It also fails to take into account environmental factors that may lull consumers into a false sense of security. For example, if it says you're genetically less likely to be in danger of heart disease, but you are eating an unhealthy diet, the danger of heart disease may remain even stronger than normal.
Currently, most physicians are unable to properly interpret the results since the technology is so new and complex. There is no national program that educates the public about genetic results, nor is there a common curriculum or training to interpret genomic testing results in healthcare education.
If, however, you're just interested in doing it for recreational reasons, like finding ancestry information, then that it likely harmless.
Personalized genomic information is definitely the future of medicine, but it just may not be appropriate right now when there is such a lack of information.
I was thinking some of these things, R54. But if enough people pay into the system, it can only get better. I want to do it solely for disease info, and find out if my hunches are right. My partner is also quite a bit older, and if there are things we can research and change in our lifestyle to address potential problems we carry, all the better, right?
Thanks for the responses, they were very helpful. I think I'll check out ancestry.com just to see what it's all about. And I'm assuming that R48 is only talking about the DNA tests and not simply signing up for the site, correct?
Hey, R42, that's a very interesting story you've got there. I definitely think you should consider the DNA test and then possibly genealogical research on your family ( if you haven't already done so). I think the DNA testing will definitely help you get started on that. Your ancestry is so interesting that I'm sure you'd uncover some great stories. 23andMe will pretty much just give you an ancestral painting, your maternal, and paternal line, and then the health risk, and traits.... I'm going to read up on the African Ancestry test to see if it's something I might be interested in. Thanks for your reply.
23andMe and Family Tree DNA are both reputable and far better than Ancestry.
I tested with both 23andMe and FTDNA. This gives me many more matches because there are different people on each of them.
Both 23andMe and FTDNA will tell you if you have African ancestry.
R31 They don't always drill down into specific countries per se because what they're saying is: Your genetic material matches other people in this haplogroup. Which doesn't always neatly stay within a country's borders.
Also, think about how many times in the last 1000 years alone European countries have changed borders!!
The reason I believe in both tests is that I found people who were distant cousins where, after exchanging information, we had a common ancestor. So the test correctly identifies them as sharing a common ancestor before we confirm it. That was what gave the tests credibility, in my eyes.
I did the Ancestry.com test and then fed the raw results through GEDMatch. Then I had a bunch of choices to select from to run tests. There are many graphs to look at that I didn't post. I couldn't make much sense of the results from their predisposition to medical conditions analysis. On Ancestry.com I now have around 50 DNA matches to people on my tree that share ancestors in my tree. It works because I had a cousin take the test, too and he popped in my results about a month after his results posted.
I want to take the 23andMe test, too.
I also proved who my true Grandfather was through the DNA test. Here's the blog I wrote about it. I get new shared ancestor ancestry.com matches to my Shoeboots line because it must be a unique marker.
I did 23andme by ordering two tests: one for me and one for my dad. I waited until I had my results back to send my dad his test, in case something came up that would blow his 80 year old mind.
We show up as 99.9% European, which surprised me because both sides of my family had ancestors who arrived in Virginia in the 17th century, and were slaveholders. My paternal grandmother's family arrived in rural New England during the colonial era too, so I expected some Indian or Sub-Saharan African genes.
Based on some of the names way back in my family, their involvement in the Crusades, and their history of alternating between piracy and the British Navy I also would have expected some North African or middle eastern ancestry. That shows up as the .1%, so small it could just be anomalous.
Things I found out:
1) My parents aren't second cousins once removed, as one family legend had it. In fact for having ancestry all over the same three or four counties over a period of centuries, they're totally unrelated;
2) My dad is part Italian, which we did not know about, as close as a great-grandparent;
3) My mother has a weird strand of something that keeps changing from Finnish to Eastern European to Ashkenazi;
4) My dad is 100% Euro, and a lot more Neanderthal than my mom (I'm 2.4%), but he has African American 3rd cousins in Mississippi;
5) My dad, through his father, has the "Niall of the Nine Hostages" marker for very old Irish ancestry;
6) both parents' families are much more continental Euro than we'd always thought prior to my sister doing a huge decade-long genealogy project, but the results fit my sister's data. My grandparents all thought they were Scottish. They aren't.
7) it looks like I'm going to die of esophageal or stomach cancer. Unlike my dad, I don't have the centenarian gene - he probably blew his by smoking for 50 years.
It was interesting. I'd do it again.
Oh I see, R58. This is all beginning to make a lot more sense to me. In retrospect I realize how silly it was for me to think that European ethnicities ( or ethnic/racial identity in general) would fit neatly within a country's border, particularly when considering my own background.
The border changes and Germanic invasions, inter-ethnic mixing for thousands of years...just sort of slipped my mind (Ha!). The Haplogroup for my paternal line is I-M253 And I read that it is a Nordic European Haplogroup which may have originated in Denmark. And as I mentioned in previous posts my parents are black/Creole so it's pretty crazy. This stuff is fun and so fascinating. Although, I do wonder why my paternal Haplogroup is European while my mother's is African ( among other things)?
R57, Did you get the same or similar results with both 23andMe and FTDNA? FTDNA seems interesting and I think I might test with them.
R60, your blog is so interesting and very informative. Thanks for taking the time to do all of that and help those of us just starting out. This is a great thread.
Your results are pretty interesting and probably a bit unusual, R61. Your family can be traced pretty far back and you're results show 99.9% European is pretty surprising. The "Niall of the Nine Hostages" marker is really cool. We're so lucky that we're able to do things like this and find out such interesting things about our backgrounds and ancestors. And finding out if old family stories are accurate is pretty fun.
I want to get started on my own genealogy project but I've been putting off for so long now. But I should just bite the bullet and go for it. I wonder just how many families whose ancestors arrived in the states in the 1700s are as much as 99.9% European? Definitely a minority. A good buddy of mine tested with 23andMe around the same time that I did and his ancestors also arrived in the states in the 1700s and his results came back around 84% European with both African and Asian (basically Native American) and he was so excited about it. He thinks it means he's exotic lol. It was pretty cool.
Just last week I reconnected to a bunch of cousins I had not seen since 1968 - even though they live here in Austin and Baton Rouge. I'd been trying to find them for years without success and we found each other on ancestry.com, which has huge value in that reuniting families. I have met many distant relatives, too.
Two days ago there was an article about the discovery of a silver Viking ring. It mentioned Thorfinn the Skull Splitter, a Viking Earl of Orkney, who was one of my ancestors. Thorfinn is a huge joke in my family and among my friends now - I look like a Thorfinn - most of us in my family look like Vikings, I guess. We have adopted Thorfinn as our family mascot.
Ancestry.com enabled me to trace our family way, way back. How reliable it is back to 6th century Norway and ancient Rome I don't know (my tree gets back there). They say we are all ultimately related to Eleanor of Aquitaine and Charlemagne and not to make too much of these appearing in your tree. I have them as well.
I was fortunate to have a clear branch of my family that took me to the Earls of Orkney - and their records taking me back to 500AD are excellent through the Orkney Saga and church records.
I did the DNA test much later than I started the tree - it was essential to prove my lineage on several lines way back to the early 1600's in America and even beyond into Britain, Ireland and Scotland.
R64, my sister found the link that takes us back to Charlemagne, too. It's true most if not all of Europe is descended from him; the question is really whether you can find the line. Mine goes back to enough male lines and recorded female lines to the Angevins. Then it's pretty well recorded from there. It was fun to find it.
My dad's family turned out to be cadet Hohenzollerns. Which is funny because it also clarified an old family legend involving how the ancestors lost a lot of land in the American revolution. They came over with a wave of excess Hanoverians and were not well liked after independence. The story had morphed into Dispossessed Scots by the time my dad was told.
R65 is r61.
I didn't care about my Texas and Southern ancestry until a couple of years ago when my brother and his wife came to visit me in Austin from Seattle. I wanted to take them to Valley Mills to see our great-grandparents grave - so I had bone up on family history beforehand and that lead me to ancestry.com.
I didn't listen so carefully to many of the stories my family told - it wasn't important to me - now I wish I had written stuff down.
My grandmother in Virginia used yo talk about us being descendants of a Pocahontas; but I always thought that was a silly story that couldn't be true - well I was wrong on that one.
Has anyone else noticed that 23andMe suddenly has a commercial in very heavy rotation lately? I never noticed that before. I suppose they're advertising that $99 special OP is referring to ( by the way OP have you decided to go ahead and test with them?) I purchased it when it was $299 and that was considered a good deal at the time lol. If only I had waited. But I feel it was worth it though. But damn, $99! lol
R42, I'm just getting around to the African Ancestry website and it looks great! I wasn't aware that this was the service used on the Henry Louis Gates program "African American Lives." I really enjoyed that program, it was so compelling and enlightening with a touch of humor thrown in. A friend of mine told me that Vanessa Williams appeared on the program , but I have my doubts as I did a quick Google search and nothing came up.
A lot of Creoles swear that she's Creole ( my friend being one) and have believed so since she appeared on the scene in that beauty pageant; however, this belief is based purely on her appearance. It's very interesting that she actually did an ancestry test and publically released her results. I don't remember what they were but I don't think she's Creole but based on her ancestry I can understand why she looks like she could be.
Anyway, I went off on a little tangent there. Do you know anyone other than your father who did the AA DNA test? I would love to find out what my African ethnic group is, that would be unbelievably, no words kind of amazing! I know quite a bit about my European ancestry/ancestors ( still learning a lot though)but virtually nothing about my African ancestry ( for obvious reasons I suppose) it would be shocking to learn the country let alone the ethnic group! It's very likely that I'm going to do the AA DNA test but I suppose it's best to keep my expectations at reasonable level.
R69 google Vanessa Williams ancestry. She did an interview piece about it. She's mixed race.
I have to admit I'd never heard about 23andMe until I saw this thread. I knew about ancestry.com and other DNA tests, but not this one. So after checking into a bit, I went ahead and ordered the kit last week. It's already arrived and I sent my saliva back yesterday. I'm looking forward to the results-- both the health information and the ancestry stuff. (I was surprised how long it took to fill up the tube to the line ... and I'm a heavy salivater!)
Whoever posted this thread originally--thanks! And maybe you should get a kickback from 23andMe!
One thing I'm curious about, though-- while it was quite easy to order the kit on their website, I also checked into it on Amazon (to see if it was available under "Prime") and they said it wasn't for sale at all (even though there is a listing there.) Anyone know why?
Coolest thing I learned from the test was that I am heterozygous for the CCR5-delta32 gene, giving me some resistance to HIV and a slower progression to AIDS should I become infected.
You can't do it in New York. You need to have an out-of-state address. Bummer.
R73 Well you only need the address to receive the kit; after that everything is online. Don't you know someone in a nearby state? At least in the most populous areas of, you probably work or interact with people from CT, NJ, or PA fairly often, no? (Not like California, for sure!)
[quote] Don't you know someone in a nearby state? At least in the most populous areas of
insert "New York" after "of"
That's strange. Why would they not allow people in New York to participate? I don't understand that.
That is cool , R72! Well, according to my results, I'm resistant to MPB ( male pattern baldness). It's not as cool and interesting as yours but at least I'll have my hair, ha!
R76 Some states have health information and/or privacy laws that preclude the sale of this type of testing. Apparently it was a problem in California as well, until recently when they did something to allow it to be in compliance with their rules and regulations.
You can get the test in NYC.
The only issue is that they don't allow it to be MAILED BACK from a NY address.
So you can jump on the PATH and get out on the first stop into NJ to mail it from the Hoboken Post Office, which is three blocks from the train.
This is what I'm planning to do...
The medical info I got from 23 and me was much more interesting/valuable than the ancestry stuff because I am cajun and ALL cajuns are related to each other if you go back far enough. I got so many requests from 4th and 5th cousins that I finally turned off that part of the service. I still have not gotten the courage to unlock the part that tells how likely it is that I will get Alzheimer's. Someday.
R78 How on earth would they possibly know or care if it's mailed back from NY or NJ?
It's called a POSTMARK, R80.
R80 When was the last time you saw a postmark on BUSINESS REPLY MAIL with prepaid postage, moron? There IS NO POSTMARK.
Oh I see R77. Thanks. At least there may be a way around it as R78 explains.
So true, R79. Some of them are so scary to click on. I got some bad news about colon cancer. But at least I know and I've changed my diet because of it. But the thing is the study was done on European men, but I'm wondering if it would also apply to people who are partially or have some European ancestry? Maybe someone here will know. I received a lot of request from cousins too, but they seem to come in groups 3 or 4.
R82, it is still stamped from the point of mailing, dumbass.
You need to get the testing to ensure you haven't made it through life this far without anencephaly.
Here's the official answer:
[quote]While 23andMe is authorized to ship sample collection kits to the state of New York, 23andMe is currently unable to process saliva samples collected in or mailed from the state of New York. The New York Department of Health considers our Personal Genome Service a test requiring a lab license and direct physician involvement. You or the recipient of the saliva kit must collect your sample and mail it from outside the state of New York. Upon receipt of your saliva kit, you or the recipient will be required to affirm under penalty of law that the sample for the saliva kit has not been collected in or mailed from the state of New York.
So, no, they don't have any way of knowing from where it was mailed; you have to swear that it wasn't mailed in NY. (Like anyone would bother to waste the resources on checking that.)
A lot of the information (most of it actually) regarding health concerns aren't yet available for non-whites as no studies have been done. Keep that in mind if you're purchasing 23andme for that reason.
Some of us might not find out we're non-white until after we get the results back!
I got a few requests from distant cousins who were adopted and trying to learn something about their ancestry. Which is kind of cool for people who know nothing about their biological families.
The scary results I got were about gastric cancers and Parkinson's - it says I have a higher risk of both. Parkinson's had to be unlocked. It also tests for (and locks the results for unless you opt in) the BRCA gene for breast cancer. I knew the results already but it was nice to know I didn't have the mutation.
The test also illustrates the difference between genotypes and phenotypes. My father has the male pattern baldness gene, according to 23andme, but at age 79 and 81 both he and his brother have thick, full hair. Genotypes only predict statistical probabilities, not certainties.
R85, they legally have to discard any kits that come from state of NY, so they'll know. They cover themselves. Maryland, can't give or receive.
I noticed that, R86. I've only seen a few for African Americans/Or SSA ( and that's a very recent addition) and maybe one study that was done on Asians. But there could have been updates since my last visit. My ancestry painting says that 53% of my ancestors came from Europe, 42% from SSA, and 5% from Asia. So a study like the colon cancer study which was done on European men wouldn't apply to me, right? I'm leaning toward no ( and hoping that it's no) but I'm paranoid.
NY state has serious regulations about a lot of things, and this must be one of them.
Buying insurance is a nightmare in NY because so few companies have offices there, and NY requires that any insurer MUST have an NY office.
I don't know if the items would be "postmarked" but based on my experience with 23andMe, the return mail kit they send you automatically already has a USPS tracking code, so YES, they WOULD be able to see where a particular sample was picked up from via tracking.
Oh I see, R90. So basically something environmental has to trigger the genetic predisposition.
For some reason I thought NY would be more relaxed about something like this. It sucks, because it's best to get lot's of people doing the test so 23andMe can give better and more accurate results. It sucks they certain states can't even participate.
That's an interesting question, R92. Do you think 23andMe might have something on the site that answers questions like that? The ancestry aspect of 23andMe is very interesting and can uncover some ancestry that you may not have been aware of. But I'm sure your results weren't all that surprising since you're biracial. I have a family friend who has always suspected that her great-grandmother was melungeon and her test results pretty much confirmed it. Her great grandmother and father looked/look Southern Italian or Sicilian but claim to be full-blooded ( whatever that means) Irish. For her it sparked a huge interest in genealogy and melungeon culture. But do check 23andMe to see if they answer questions like yours.
Question for 23andme users: I just got my results recently and found a 2nd to 3rd cousin on my matches. We shared ancestry dna and he said he thought we were cousins on a particular part of his family tree and gave me the last name of the common ancestor. How does somebody figure that out?
Mine says I have .02% Ashkenazi hardly worth mentioning right ?
I don't want to be nit-picky, R96, but both of my parents are AA/Creole. I know that the term simply means a person of two different "races" but most people immediately think of biracial as having parents of two different races. My family's Louisiana Creole heritage goes back many generations and I've learned to be quite the stickler about correcting people ( Sorry about being that guy, it's like a natural reflex). But I'm sure anyone reading my posts would have reached the same conclusion that you did, so it's no biggie.
But yes I was surprised by the percentages and surprised by some of the possible ethnicities ( German, Jewish...) But I'm fine with it. I think it's more proof that race is a social construct, which is why I typically choose to identify by ethnicity such as African American or Creole.
I agree Melungeons have a very interesting history, how exciting for your friend. It sounds like her great-gran is no longer with us? Thank goodness for technology. My great-grans sister ran away to live as white. The odd thing is she came from an affluent, well educated family. She was also engaged to marry a Creole banker ( and based on the pic he was very handsome) who came from a very good family. My great-gran said that she just ran away one day. She left her family a letter saying she was going to NYC to be happy ( She hated Jim Crow but who wouldn't?). She wrote them periodically and she supposedly married a wealthy Jewish man and had children. I've never met her ( I've seen pictures and she was a beauty, she looked almost identical to my great-gran), I don't even know if is she's still alive( my great-gran passed 2 years ago). Gosh, I'm writing too much. I just really love this thread.
Wow! R97, those are some pretty close cousins. I'm not sure how they figure out a common ancestor, maybe they've already started the genealogical process. Honestly, I'm such a bitch that I never respond to any of my cousins. I should start responding, you never know what you could find out about your ancestry.
[QUOTE] Question for 23andme users: I just got my results recently and found a 2nd to 3rd cousin on my matches. We shared ancestry dna and he said he thought we were cousins on a particular part of his family tree and gave me the last name of the common ancestor. How does somebody figure that out?
He may be guessing, but 23andMe can also identify haplogroups (complex to explain, but it groups people of likely similar DNA together) and he may have made a guess or an estimate based on your haplogroup.
I kind of have this fear of doing something like this and then getting a report that "your DNA isn't completely human" or something. I know that's a weird thing to worry about but ... well, if you knew my family ...
R102 - well, it actually does show if you have neanderthal genes or not. So...
Did you ever find out the answer, R92? I'm Eurasian here and I'd like to know that answer as well. If any of you decide to do the genetic testing with 23andMe just be prepared for the possible disease/illness section.
Just sent in my spit. I was able to preview the sections when I registered online - it was pretty amazing how many hundreds of pieces of data you get about so many things.
Granted, most of these items will probably come back in "normal" range, but to know that it's been somewhat tested is truly astounding.
Will let you know in a few weeks...
I did the ancestry one at the beginning of the year. It wasn't that much help except to confirm that a 2nd cousin I connected with on Ancestry is indeed my second cousin. Apparently at some point in my grandfather's life he distanced himself from his siblings who turned the family business into a huge multinational company. So I ended up only knowing the poor relations.
My cousin has the markers for breast cancer and all of the women in her family died from breast cancer. Her grandmother and my mother were cousins. She had the same surgery as Angelina Jolie because of it.
Am wondering if this test would provide more info since I know next to nothing about my family.
I think Michelle Obama did one too, R70. I don't know what her results were, though. Genetic testing seems to be gaining in popularity.
just received my collection package today, but have decided against proceeding. why? the fact that disability insurers can discriminate on basis of genetic testing. they can ask for result of any genetic tests that you have had, and use them for underwriting purposes. apparently that does happen in europe. am i over-reacting?
I think you are absolutely right to be concerned about that, R109. It's just not worth taking that chance.
R109 I thought about that, but since I have health insurance coverage for life through my former employer (I'm a federal government retiree) I figured it was worth the risk. And of course Medicare doesn't look at that information either (when I become eligible.)
I have no interest in finding out I'm related to Kunte Kinte, Genghis Khan or Honey Boo Boo.
I prefer to think of myself as a garden variety mongrel with the self-preservation of a feral cat.
To those of you who have decided to do any of the many genetic tests out there please share your results once you get them. I love reading about some of the things that surprise people about their results. Well, I mean only the things you're comfortable sharing of course.
Disability insurers? How would they get a hold of your results?
I want to do this now.
R113, information is bought and sold. I'm sure insurers have already approached these places asking them if they can buy their customer data.
I've only tested with 23andMe and in their privacy statement it says that they won't release your information to a third party without your explicit consent.
Does the report include percentage of Denisovan DNA? Apparently some people have up to 6% Denisoven DNA, or as much as 4% Neanderthal DNA. (But not usually both.)
You need to google recent reports on the efficacy of those tests, OP. I recall reading that they were wildly inaccurate by inept labs that disappear into the night.
Sorry it took me so long to respond, R105. I was simply being paranoid and just threw that question out there just to see if anybody had some information that I was unaware of. If the testing was performed exclusively on European men, the results wouldn't apply to mixed-"race" people given that the average European American is at the very least 90% European.
I think I've seen some tests that were performed on Asian men but I'm not sure that it would apply to you since you say that you're Eurasian. However, African American would apply to me simply because the average African American has European ( and some Indigenous American) admixture ( I just wanted to point this out for lurkers and mixed-race African Americans who might be interested in doing the DNA testing). Sorry for the confusion.
Is this going to continue to be $99 you think? Because Sergey who was funding the whole venture dumped his wife for a younger Asian/Jewish girl with a Brit accent. Dumped the Jewish wife and the kids.
I just got my results back and it was pretty interesting. The health information was a little bit surprising ... although they indicate on the results that a lot of the findings are really not definite indicators-- at least yet. I guess some of there's still a lot of research to be done on how one's genetic makeup affects certain health situations.
Anyway, the tests indicated I had a much higher than average risk for Primary Biliary Cirrhosis and Celiac Disease, although both were still very low (less than one-half of one percent.) It said I have a high risk for Atrial Fibrillation (46.9% v. 27.2% for the average person.) The other ones with elevated risks were Alzheimer's and Macular Degeneration. All of these results were from the "four-star" category, which means they've been fairly well-researched and they have the most confidence in the results.
The family/ethnicity thing was pretty much as expected. They try to figure out where your lines were around 500 years ago, before there were so many mass migrations. The closest relatives they found (among their participants) were two second cousins.
Wow!, R121, Alzheimer's and Macular Degeneration is pretty scary. I would be so freaked out.
[quote] simply because the average African American has European ( and some Indigenous American) admixture
This isn't true. Very, very few African Americans have Amerindian DNA. Henry Louis Gates has found that almost no AAs he tested who claim to be part Amerindian have Amerindian DNA. Apparently, Native American princesses are to AA lore what Celtic kings are to white people. Something that makes the past seem a lot more romantic than it was.
Interesting. FDA halts sale of 23andme. Who could have ever seen that coming?
I was going to get it for a family member (black friday sale).
That sucks. It actually accurately noted a family member had hemochromatosis which had reached life threatening levels. We would have never had a test for it otherwise.
@r125 Dr. Gates says a lot of things. He tends to over generalize. I tested with him and most of the major companies. I have over 900 DNA cousins, half of which are African American (like me) and most have a little NA. Some have NA haplogroups (only a handful). I do notice that more AAs tend to have NA than European Americans. Oddly, a few of my European cousins (born in Europe) show a little NA, I think they're picking up on Finnish ancestry and the like, or West Asian).
I've found that some of the people with higher NA, whether they're European or African American, are the ones who aren't expecting it. Many people have stories about full blooded grandparents and show very little or zero NA blood.
23andme released a statement saying "We recognize that we have not met the FDA's expectations regarding timeline and communication regarding our submission. Our relationship with the FDA is extremely important to us and we are committed to fully engaging with them to address their concerns."
They're not going anywhere.
Dr. Gates had that dreadful genealogy show in which he took great pride in telling "white" people they had negro blood in their line. He is a white wanna be. He has a big chip on his shoulder we call "militant inferiority."
Why are you people paying someone to use your DNA at a crime scene which implicates you?
And why are you giving your DNA to the government spooks?
Also, why are you setting yourself up to be exploited and denied by insurance companies?
Here, you want info on your heritage? go do your own genealogy research. Or pay someone to do it for you.
Want to to know if you have Indian blood? Check your teeth, it's called shovel teeth. You may have a bump on the back of your head as well.
Yes, you can be a fair-skinned blond and have black ancestry, skin color is not a determinate, and if your family has been here for 300 years or so you are likely to have black and/or Indian ancestry. It's not rocket science, people.
R132, I'm sorry, but there's no such thing as genetic privacy. If someone wants to profile you genetically badly enough, they can do it. Everyone time you get your hair cut, your blood tested, your teeth cleaned, every time you throw away a piece of gum or a cigarette butt, you're potentially placing your dna in someone else's hands.
For instance, a serial killer in CA was convicted based on dna evidence obtained from a half-eaten slice of pizza he left at restaurant.
There IS an expectation of genetic privacy when I go to the dentist or doctor, R133, and if I ever found out he was giving up my DNA to anyone I would go public and sue. And they would lose their license, no doubt.
What people are doing is willfully submitting their DNA to a company whom you don't know will do what with the info. And, to top it all off, you are paying for it.
Like I said, there are people out there who are professional genealogists who need to pay their bills and are quite good. that's a much safer way to go.
[quote]What people are doing is willfully submitting their DNA to a company whom you don't know will do what with the info.
Not true. You know exactly what they do with it. They have a privacy agreement, and they do nothing with it unless you specifically ask otherwise.
They also have a research program where they amalgamate a bunch of people's results and try to correlate dna with medical conditions as reported on user surveys. They may publish their findings, but not before the findings are stripped of all identifying information. This research program is opt-in only. You can have full access to 23andme's services without opting in.
Well, then, how about saving yourself all that money and just stick to a healthy diet and exercise LOL.
And you believe them, why, R135?
I remember catching some flack here because I suggested that one shouldn't be submitting their personal information on that roughshod Obamacare website. Well lookee here, I was right after all.
Can they test for what R136 has?
Tattoos and DNA 'testing' are great ways to let others identify and keep tabs on you without your knowledge.
It's weird that so many fall for this.
[quote] Dr. Gates says a lot of things. He tends to over generalize
It was on his show. Every AA he tested who claimed Native American background lacked Native American DNA. He didn't make that up, it's a fact.
In the UK the police have been caught taking people's DNA from random stops and now in the US the police have been forcing blood tests on random drivers in Texas.
I've always thought a good way to mess up DNA at a crime scene would be to sweep up the stuff on a hair salon's floor and scatter it about the scene.
Most AA people do not have Indian blood because honestly, they were forced to work with Irish slaves and even 'mated' like horses with Irish women. They really didn't come in contact with natives at all. And regarding the Cherokee, well, the Cherokee had black slaves themselves and fought for the confederacy.
So, AA have Irish blood either through rape or working closely with Irish slaves.
For the same reason you assume your doctor won't share his access to your dna with anyone. They'd be opening themselves to lawsuits.
Not that it matters in the slightest to me. I've been tested by 23andme and have freely shared my data with third party researchers and genealogists. I understand the illusive nature of genetic privacy and don't let misconceptions get in the way of the potential benefits I can receive from dna analysis.
Among them, I've been able to rule out a purported relationship with another family who shares my surname. I also understand I'm at highly increased risk of macular degeneration, and though it's not a condition I've developed yet, I am being monitored for it, and have changed my diet to include more of the leafy greens known to be protective.
We are all at risk for macular degeneration, and everyone should be eating greens. Taking melatonin helps I hear, as well as Bilberry.
Again, I question the value of the "medical breakthroughs' of this company. I smell bullshit.
Those of us with European ancestry who share a particular allele of the CFH gene are roughly 3 times more likely to get macular degeneration than others.
I have an elderly relative who shares this allele with me, and he's already developed the condition. Genetics has a real impact on health, which I've seen in my own family. I'm grateful to 23andme for making this knowledge accessible to me.
DNA data mining backed by Google & Big Pharma money. Yea...that'll end well.
R143, that's inaccurate. The vast majority of European admixture in AA's came after slavery.
R125, according to Ancestry.com the average AA is 65% SSA, 29% European, and 2% NA ( which is probably why the poster you replied to used the word "some").
Email I received today.
Dear 23andMe Customers,
I wanted to reach out to you about the FDA letter that was sent to 23andMe last Friday.
It is absolutely critical that our consumers get high quality genetic data that they can trust. We have worked extensively with our lab partner to make sure that the results we return are accurate. We stand behind the data that we return to customers - but we recognize that the FDA needs to be convinced of the quality of our data as well.
23andMe has been working with the FDA to navigate the correct regulatory path for direct-to-consumer genetic tests. This is new territory, not just for 23andMe, but for the FDA as well. The FDA is an important partner for 23andMe and we will be working hard to move forward with them.
I apologize for the limited response to the questions many of you have raised regarding the letter and its implications for the service. We don't have the answers to all of those questions yet, but as we learn more we will update you.
I am committed to providing each of you with a trusted consumer product rooted in high quality data that adheres to the best scientific standards. All of us at 23andMe believe that genetic information can lead to healthier lives.
Thank you for your loyalty to 23andMe. Please refer to our 23andMe blog for updates on this process.
Co-founder and CEO, 23andMe