A lotion that cures male-pattern baldness could be for sale in as little as two years. University of Pennsylvania dermatologist George Cotsarelis says the lotion works by inhibiting a single enzyme, prostaglandin D2 (PGD2), which he says is the "major" enzyme connected to hair loss.
And the cure would also extend to men of all ages who have already lost their hair.
"We really do think if you remove the inhibition, you get longer hair," Cotsarelis told the journal Science Translational Medicine.
Cotsarelis and his team of researchers first applied the lotion to mice and found that it was effective in both stopping hair loss and in regenerating follicles that had already ceased to produce longer hairs.
"During normal follicle cycling in mice, Ptgds and PGD2 levels increase immediately preceding the regression phase, suggesting an inhibitory effect on hair growth," the study reads. "We show that PGD2 inhibits hair growth in explanted human hair follicles and when applied topically to mice."
Cotsarelis says he is currently shopping the lotion to several U.S. drug firms and hopes the product can be sold publicly in the near future.
He says that there are already prescription antiasthma drugs available, which work by reducing PGD2 levels. The presence of those treatments should help accelerate the baldness cure's availability in stores. The transition from discovery to potential product has already been a rapid one, as the study results were only first announced in March.
"I can't see why we won't soon be able to intervene to prevent hair loss," Des Tobin, the director of the University of Bradford Centre for Skin Sciences told the Telegraph, calling the study "a big step forward."
They're waiting until I'm completely bald before they put the cure out there.
This is a definite step forward. Usually a baldness cure is about 5 or 10 years away from tomorrow, and tomorrow never comes.
Safe for ballsacks?
Great news for us eldergays ... eventually. Considering the market for this, it will be hugely expensive as long as the patents last.
"it will be hugely expensive"
If it truly works (and not just Propecia-like effectiveness), then people will complain about the price, but pay. They'll mortgage their homes and pay.
WEHT the stem cell cure? I've been waiting for that for 5 years already.
if you've seen jason alexander lately, I think he got in on the trials.
Great. Wake me when they cure cancer.
I, for one, am not celebrating this. I love a bald man.
Will it work on a completely bald head or is it like Propecia where it would only keep the hair you have?
Yes, R6, those who can certainly will.
What the drug company will do is set the price so it is high enough for them to make an obscene profit, and just high enough for consumers to reluctantly but willing pay the price.
Did you read the article, R13?
[quote]And the cure would also extend to men of all ages who have already lost their hair.
Tutti a tavola a pettinarsi!
OK that was strange. At R15 I seem to be replying to myself at R13 with an unrelated comment, but I swear there was another post I was responding to that isn't showing up for me now. Maybe the board will sort itself out soon.
If it's based on an existing drug then a generic version could possibly be made.
Here's the positive and negative part:
1) Positive: The drug is already being prescribed in pill form to treat other conditions. It's passed the FDA review, so it might be faster to get it approved in lotion form. It's not some new, unknown drug.
2) Negative: No human trials, no concrete results, just a university-affiliated dermatologist shopping around a drug/cure to big drug companies.
So we can remain hopeful, but skeptical until trials on humans are performed.
I like male-pattern baldness
I'm going to buy a jug of the stuff and force my way into porn studios to lather up all those barren crotches.
Yeah, but the side effects will be that you're balls shrivel down to raisinette size.
I guess I understand this but I'm kind of shocked that so many view this as a great thing.
I think that bald or partially bald men are really handsome.
No, I didn't read the article. TL;DR.
What did it say?
Who cares, I don't need it.
One's doctor knows which asthma drugs are described in the artcle. No one needs to wait for the high priced lotion. I've used minoxodil for 28 years and started when I had to buy the pills and have the pharmacist compound the stuff in a solution.
It'll cause cancer. Don't you worry 'bout that!
R25 you are awesome!
[quote]We really do think if you remove the inhibition, you get longer hair,"
That's all the proof I need...somebody who THINKS something will work without any scientific data proving it. As long as someone thinks it then it is a fact!
There have been lots of new medicines, promising miracle results for many problems, that never work.
If they have genuinely invented a medication to reverse pattern baldness, buy stock in the company, it is a practically a license to print money.
A cure for baldness? I didn't know it was a disease.
I just use the other end of my NO NO for more hair.
It would be great thing if it happens in near future. People are wondering really whether there is a proper treatment for baldness cure or not.